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They have a similar risk for inducing weight gain as sulfonylureas do but possibly carry less risk for hypoglycemia.

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Consequently, patients and clinicians have been faced with difficult decisions on the use of these drugs, which are often prescribed to patients with type 2 diabetes whose response to other oral agents is suboptimal but who are reluctant to start insulin.

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Pero tenemos que recomendarle consultar con su médico antes de tomar este medicamento.

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Glimepiride was non-mutagenic in a battery of in vitro and in vivo mutagenicity studies (Ames test, somatic cell mutation, chromosomal aberration, unscheduled DNA synthesis, and mouse micronucleus test).

Enthusiasm for the potential benefits of pioglitazone and vitamin E must be tempered by the finding that there was an improvement in histologic features in only 34% of the subjects who received pioglitazone and 43% of those who received vitamin E, and steatohepatitis resolved in only 47% and 36% of the subjects in those two groups, respectively.

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The recommendations in this position statement will obviously need to be updated in future years in order to provide the best and most evidence-based recommendations for patients with type 2 diabetes.

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The balance of efficacy and safety of TZD varies widely from patient to patient.

Of these, 48 trials met the predefined inclusion criteria of having a randomized comparator group, a similar duration of treatment in all groups, and more than 24 weeks of drug exposure.

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Actos works by helping to control blood sugar levels in people with type 2 diabetes, but diabetes treatments focused solely on lowering blood sugar can actually worsen, rather than remedy, the underyling metabolic dysfunctions at the root of type 2 diabetes.

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Conventional treatment, which is focused on suppressing the symptom of elevated blood sugar rather than addressing the underlying causes, is doomed to fail in most cases.

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Easily compare tier status for drugs in the same class when considering an alternative drug for your patient.

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Beta-blockers, clonidine, lithium salts, and alcohol may either potentiate or weaken the blood-glucose-lowering effect of insulin.

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Glimepiride is usually taken once daily with breakfast or the first main meal.

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One medication in this class, pioglitazone, may reduce the risk of cardiovascular events, including stroke, in patients with type 2 diabetes, for whom the drug is currently approved as a glucose-lowering agent.

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